MuSK(Phospho Tyr755) Polyclonal Antibody, 50ul Capsule Filter Diseases associated with PRAF2 include

Diseases associated with PRAF2 include neuroblastoma

NRTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

The consensus recognition site is 5'-T

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

The encoded protein is a transcription factor important for the development of the renal and urogenital systems

MuSK(Phospho Tyr755) Polyclonal Antibody, 50ul Capsule Filter Diseases associated with PRAF2 includeThis gene encodes a muscle specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.