CSPP1 Polyclonal Antibody, 100ul Bottle-Top Dispenser Cells with reduced levels of

Cells with reduced levels of ACAP1 or AKT1 and AKT2 show inhibition of stimulation-dependent cell migration

the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death

Deficiency of the encoded protein has been associated with herpes simplex encephalitis

Interacts with DAB2IP and SIAH1 (By similarity)

This pseudogene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7

CSPP1 Polyclonal Antibody, 100ul Bottle-Top Dispenser Cells with reduced levels ofThis gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.