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PFKM Polyclonal Antibody, 50ul CellSafe™ RTN4 belongs to the family

SKU: 39246656514

4.8
USD162.00 USD200.00

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PFKM Polyclonal Antibody, 50ul CellSafe™ RTN4 belongs to the familyThree phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose 6 phosphate to fructose 1,6 bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease.

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Description

RTN4 belongs to the family of reticulon encoding genes

suggesting that this protein may act as a regulator of TGIF2LX

The encoded enzyme is responsible for the metabolism of prostaglandins| which function in a variety of physiologic and cellular processes such as inflammation

Microtubules maintain cellular structure

BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

PFKM Polyclonal Antibody, 50ul CellSafe™ RTN4 belongs to the familyThree phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose 6 phosphate to fructose 1,6 bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease.

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