CYLD Polyclonal Antibody, 50ul Peptide Synthesis Could be E3 ubiquitin-protein ligase

Could be E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles

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DVL2 and/or DVL3)

This gene encodes a member of the secretoglobin family of small secreted proteins

CYLD Polyclonal Antibody, 50ul Peptide Synthesis Could be E3 ubiquitin-protein ligaseThis gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.