PMGT1 Rabbit Polyclonal Antibody, 20ul ADME is a 551 amino acid

is a 551 amino acid multi-pass membrane protein that belongs to the chloride channel MCLC family

This protein forms a heterodimeric complex and binds and activates| in a glucose-dependent manner| carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes

Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB)

This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis

Among its related pathways are Transmission across Chemical Synapses and Potassium Channels

PMGT1 Rabbit Polyclonal Antibody, 20ul ADME is a 551 amino acidThis gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle eye brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.