Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables These apparently intronless genes encode

These apparently intronless genes encode a 7-transmembrane receptor protein

The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2| and expression of this gene may play a role in malignant transformation

but the full length nature of some of these variants

Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions| while up-regulation of this gene has been observed in colorectal cancers

Preferentially binds the chromophore 11-cis retinal and is a bistable protein that displays emission peaks at 380 nm (UVA light) and 470 nm (blue light) (PubMed: 22043319)

Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables These apparently intronless genes encodeABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed: