NTAN1 Rabbit Polyclonal Antibody, 100ul Sampling Tubes Mutations in this gene have

Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome

An essential function of a modified proteasome

which contains five ANK repeats and belongs to the POTE family

This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12

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NTAN1 Rabbit Polyclonal Antibody, 100ul Sampling Tubes Mutations in this gene haveThe protein encoded by this gene functions in a step wise process of protein degradation through the N end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N terminal L Asn residues on proteins to produce N terminal L Asp. L Asp substrates are subsequently conjugated to L Arg which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of