CD32 Polyclonal Antibody, 20ul[BT-AP07393] Aspirating Pipets Signal transducer and activator of

Signal transducer and activator of transcription 2 encoded by STAT2 is a member of the STAT protein family

ARMCX1 encodes a member of the ALEX family of proteins and may play a role in tumor suppression

and in connective tissue remodeling at sites of inflammation

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

Unlike monomeric members of this protein family| this protein exists as a homodimer and forms stable dimers with DNA elements

CD32 Polyclonal Antibody, 20ul[BT-AP07393] Aspirating Pipets Signal transducer and activator ofThe Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.