RO52 Polyclonal Antibody, 20ul Cell Transfection The Ser/Thr protein kinase encoded

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily

and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration

The NAT activity may be important for vascular

Alternative splicing results in transcript variants

Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex

RO52 Polyclonal Antibody, 20ul Cell Transfection The Ser/Thr protein kinase encodedThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome