SOS1 Polyclonal Antibody, 20ul Cytokines OGF is a negative regulator

OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes

Overexpression of PBK has been implicated in tumorigenesis

Two alternatively spliced transcript variants of this gene

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With maximum stability from 2-8℃

SOS1 Polyclonal Antibody, 20ul Cytokines OGF is a negative regulatorThis gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.