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GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Allelic variants are associated with

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GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Allelic variants are associated withNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and

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Description

Allelic variants are associated with prostate and brain cancer susceptibility

The encoded proteins also lack a C-terminus RING finger domain

and is thought to be a mediator of EBV effects on B lymphocytes

The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

GR Polyclonal Antibody, 100ul[BT-AP03790] Antibodies Allelic variants are associated withNR3C1 encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and

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