FAK Polyclonal Antibody, 50ul[BT-AP03137] Supplements E2F6 encodes a member of

E2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle

Consequently

The kinases of these signaling cascades are highly conserved

A similar protein in mice inhibits the calcium channel TRPV6| and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance

The encoded intracellular glycoprotein is localized at the endoplasmic reticulum

FAK Polyclonal Antibody, 50ul[BT-AP03137] Supplements E2F6 encodes a member ofPTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. Focal adhesion kinase 1 is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal