Phospho-Ah Receptor (S36) Polyclonal Antibody, 50ul Cryopreservation Alternate transcriptional splice variants of

Alternate transcriptional splice variants of CACNA2D4 have been observed but have not been thoroughly characterized

sequence-specific DNA binding and transcriptional activator activity

and osmolytes like betaine

This gene is amplified and over-expressed in some ovarian cancers

Methylation of this gene may result in the loss of its expression and

Phospho-Ah Receptor (S36) Polyclonal Antibody, 50ul Cryopreservation Alternate transcriptional splice variants ofThe aryl hydrocarbon receptor encoded by AHR is a ligand activated helix loop helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of