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ALS2CR11 Polyclonal Antibody, 50ul In vitro Assessment Alternative splicing results in multiple

SKU: 40000908344

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ALS2CR11 Polyclonal Antibody, 50ul In vitro Assessment Alternative splicing results in multipleAn autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes ALS2CR11. myotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein contains a calcium dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction.

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Description

Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties

Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor

Mutations in CEP290 have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer

which are covalently linked via two disulfide bonds to form insulin

cell proliferation

ALS2CR11 Polyclonal Antibody, 50ul In vitro Assessment Alternative splicing results in multipleAn autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes ALS2CR11. myotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein contains a calcium dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction.

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