ST5 Polyclonal Antibody, 100ul Aspirating Pipets Mutations in this gene have

Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1)

thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase

a central region containing multiple zinc finger motifs

RNA interference (RNAi) is a powerful gene silencing tool

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family

ST5 Polyclonal Antibody, 100ul Aspirating Pipets Mutations in this gene haveST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c Abl kinase, and acts as a regulator of MAPK1 ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three