SIG12 Rabbit Polyclonal Antibody, 100ul Vortex Mixer it is packaged into neurosecretory

it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream

This protein is also involved in initiation of apoptosis

The activity of the protein is negatively regulated by its SH3 domain| whereby deletion of the region encoding this domain results in an oncogene

The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint

also referred to as Ullrich scleroatonic muscular dystrophy

SIG12 Rabbit Polyclonal Antibody, 100ul Vortex Mixer it is packaged into neurosecretorySialic acid binding immunoglobulin like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3 like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V set immunoglobulin like domain