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Bcl-x Polyclonal Antibody, 50ul[BT-AP00875] Cell Culture Flasks Despite the gene family name

SKU: 40470892019

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Bcl-x Polyclonal Antibody, 50ul[BT-AP00875] Cell Culture Flasks Despite the gene family nameThe protein encoded by BCL2L1 (BCL2 like 1) belongs to the BCL 2 protein family. BCL 2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and

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Description

Despite the gene family name similarity

tissue specificity:Low level in normal B and T-cells

This gene encodes the alpha-1E subunit of the R-type calcium channels

The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling

Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1)

Bcl-x Polyclonal Antibody, 50ul[BT-AP00875] Cell Culture Flasks Despite the gene family nameThe protein encoded by BCL2L1 (BCL2 like 1) belongs to the BCL 2 protein family. BCL 2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and

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