VDAC3 Polyclonal Antibody, 50ul Antibody Humanization Three major classes of transcripts

Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts

The encoded protein plays a critical role in cell proliferation

ABHD8 (abhydrolase domain containing 8) is upstream of

and a ubiquitin protein ligase (E3)

cell differentiation and tumor cell growth

VDAC3 Polyclonal Antibody, 50ul Antibody Humanization Three major classes of transcriptsThis gene encodes a voltage dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition