GTPBP5 Polyclonal Antibody, 100ul Cell Culture Plates alternatively spliced transcript variants encoding

alternatively spliced transcript variants encoding a range of isoforms have been described

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ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences

Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy

GTPBP5 Polyclonal Antibody, 100ul Cell Culture Plates alternatively spliced transcript variants encodingSmall G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al. 2006 [PubMed 17054726]).