FBX10 Rabbit Polyclonal Antibody, 50ul Reservoirs Among its related pathways are

Among its related pathways are Transport to the Golgi and subsequent modification and Chaperonin-mediated protein folding

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Mutations in this gene have been associated with maturity-onset diabetes of the young

The protein product is 91% identical to ubiquitin-conjugating enzyme E2N| a multi-exon gene product

tissue specificity:Leukemic stem cell

FBX10 Rabbit Polyclonal Antibody, 50ul Reservoirs Among its related pathways areMembers of the F box protein family such as FBXO10 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004