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Neu(Phospho Tyr1221/Y1222) Polyclonal Antibody, 100ul Sealing Film This gene is located in

SKU: 40769465739

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Neu(Phospho Tyr1221/Y1222) Polyclonal Antibody, 100ul Sealing Film This gene is located inThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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Description

This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer

SCF(FBXW2) directs ubiquitination of GCM1

Both N- and C-terminal domains are required for transcriptional activation

It is thought to be responsible for the 'local' production of T3

Binds to DNA sequences containing the consensus nucleotide core sequence GGAA

Neu(Phospho Tyr1221/Y1222) Polyclonal Antibody, 100ul Sealing Film This gene is located inThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those involving mitogen activated

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