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LIR-6 Polyclonal Antibody, 100ul[BT-AP05031] Inoculating Loops/Needles subcellular location:Localizes to intracellular membranes

SKU: 40813696825

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LIR-6 Polyclonal Antibody, 100ul[BT-AP05031] Inoculating Loops/Needles subcellular location:Localizes to intracellular membranesLILRA1 encodes an activating member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

subcellular location:Localizes to intracellular membranes

The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

This gene encodes a member of the WWC family of proteins| which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product

They are responsible for the generation and propagation of action potentials in neurons and muscle

LIR-6 Polyclonal Antibody, 100ul[BT-AP05031] Inoculating Loops/Needles subcellular location:Localizes to intracellular membranesLILRA1 encodes an activating member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms.

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