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IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos This gene encodes the enzyme

SKU: 40894069188

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IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos This gene encodes the enzymeInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Description

This gene encodes the enzyme homogentisate 1|2 dioxygenase

The protein encoded by this gene belongs to the actin family of proteins

The protein localizes to the nucleus and is down-regulated in some cancer cell lines

GAB2 (GRB2 associated binding protein 2) is a member of the GRB2-associated binding protein (GAB) gene family

an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-8

IL-1F8 Polyclonal Antibody, 100ul Custom RNA Oligos This gene encodes the enzymeInterleukin 36 beta encoded by IL36B is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12 stranded beta trefoil structure that is conserved between IL1A (IL A alpha) and IL1B (IL 1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

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