LRBA Polyclonal Antibody, 100ul Protein Research GAB2 is a member of

GAB2 is a member of the GRB2-associated binding protein (GAB) gene family

Expressed at higher level in heart and spleen

Interacts with KFL1 (By similarity)

and a C-terminal extracellular region with four N-glycosylation sites

AMPK subfamily

LRBA Polyclonal Antibody, 100ul Protein Research GAB2 is a member ofThe protein encoded by this gene is a member of the WDL BEACH WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder