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IL-4 Polyclonal Antibody, 100ul[BT-AP04501] Insect Expression Mutations in this gene are

SKU: 41141853451

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IL-4 Polyclonal Antibody, 100ul[BT-AP04501] Insect Expression Mutations in this gene areThe protein encoded by IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2

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Description

Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency

suggesting either heavy glycosylation or dimerization

The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity

Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions

such as ARSJ

IL-4 Polyclonal Antibody, 100ul[BT-AP04501] Insect Expression Mutations in this gene areThe protein encoded by IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2

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