Angiomotin-L1 Polyclonal Antibody, 50ul Immune Repertoire Sequencing This gene encodes a glycoprotein

This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family

The protein encoded by this gene is a component of the Hippo signaling pathway| which controls organ size and tumor growth by enhancing apoptosis

Among its related pathways are Development Slit-Robo signaling and Cytoskeleton remodeling Neurofilaments

Inhibits colony formation in cultured breast cancer cells

Contains 1 PLA2c domain

Angiomotin-L1 Polyclonal Antibody, 50ul Immune Repertoire Sequencing This gene encodes a glycoproteinAngiomotin like protein 1 encoded by AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene.