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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies designated BAI2 and BAI3 which

SKU: 4167512196

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies designated BAI2 and BAI3 whichPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures

The protein encoded by this gene regulates the DNA damage response through several different signaling pathways

Mutations in this gene cause Omenn syndrome

This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons

which belongs to the adaptor complexes medium subunits family

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07021] Organelle Studies designated BAI2 and BAI3 whichPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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