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LIN-28 Monoclonal Antibody, 100ul Antibody Humanization suggesting that it may play

SKU: 42173624216

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LIN-28 Monoclonal Antibody, 100ul Antibody Humanization suggesting that it may playThis gene encodes a LIN 28 family RNA binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of

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Description

suggesting that it may play a role in Alzheimer's disease

GIMAP2 encodes GTPase IMAP family member 2 belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins

and it is mutated in a small subset of patients with Wilms tumor

It also contains a destruction box (D box) that is required for its degradation by the APC

While it may be a target for immunotherapy| the function of this gene is unknown

LIN-28 Monoclonal Antibody, 100ul Antibody Humanization suggesting that it may playThis gene encodes a LIN 28 family RNA binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of

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