EXOS1 Rabbit Polyclonal Antibody, 50ul Recombinant Protein neurodegenerative disorder

neurodegenerative disorder

Two transcript variants| which encode the same protein| have been identified for this gene

Mice lacking this gene exhibit early embryonic death

CREB3 (cAMP responsive element binding protein 3) encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins

The protein encoded by this gene is an activator of MAP3K7/TAK1| which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK

EXOS1 Rabbit Polyclonal Antibody, 50ul Recombinant Protein neurodegenerative disorderThis gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein protein interactions with ribosomal RNA processing protein 42 and ribosomal RNA processing protein 46. Alternative splicing of this gene results in multiple transcript variants.