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MxB Polyclonal Antibody, 20ul 3D Culture 118A>G allele has been associated

SKU: 42336920667

4.0
PLN97.20 PLN146.20

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MxB Polyclonal Antibody, 20ul 3D Culture 118A>G allele has been associatedMX dynamin like GTPase 2 encoded by MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This

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Description

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy

Acts as a regulator of PCK1 expression and gluconeogenesis by a mechanism that involves

With 25 rxns at 1 rxn/μl

contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases

MxB Polyclonal Antibody, 20ul 3D Culture 118A>G allele has been associatedMX dynamin like GTPase 2 encoded by MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This

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