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SR-2A Polyclonal Antibody, 20ul Transporters one found in pancreatic islet

SKU: 42671283215

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SR-2A Polyclonal Antibody, 20ul Transporters one found in pancreatic isletHTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in HTR2A are associated with susceptibility to schizophrenia and obsessive compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant

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Description

one found in pancreatic islet beta cells and two found in liver

Mutations in CPE are implicated in type 2 diabetes

and cellular pH homeostasis

JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML)

It is prominently expressed in developing arteries but less so in adult vessels

SR-2A Polyclonal Antibody, 20ul Transporters one found in pancreatic isletHTR2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in HTR2A are associated with susceptibility to schizophrenia and obsessive compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant

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