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TF2H3 Rabbit Polyclonal Antibody, 100ul Transporters This gene and the gene

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TF2H3 Rabbit Polyclonal Antibody, 100ul Transporters This gene and the geneThis gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14.

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Description

This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y

This gene encodes a member of the Par-1 family of serine/threonine protein kinases

this enzyme may be the site of mutation in Fanconi anemia

and to a lesser degree

Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory

TF2H3 Rabbit Polyclonal Antibody, 100ul Transporters This gene and the geneThis gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14.

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