Neurofibromin Polyclonal Antibody, 100ul Capsule Filter Location-regulated scaffolding protein connecting MEK

Location-regulated scaffolding protein connecting MEK to RAF

53-regulated inhibitor of G2/M progression

The encoded protein acts as a homotrimer and is found in the cytoplasm

EphB4 (Htk)

The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan)

Neurofibromin Polyclonal Antibody, 100ul Capsule Filter Location-regulated scaffolding protein connecting MEKNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.