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CBX2 Polyclonal Antibody, 50ul CellSafe™ Customizable user setting program with

SKU: 4282314941

4.7
USD162.00 USD203.00

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CBX2 Polyclonal Antibody, 50ul CellSafe™ Customizable user setting program withCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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Description

Customizable user setting program with up to 6 sequential steps

Contains 2 protein kinase domains

This gene encodes a protein with similarity to members of the myosin light chain kinase family

Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension

Mice lacking this gene are more susceptible to bacterial infection than wild type mice

CBX2 Polyclonal Antibody, 50ul CellSafe™ Customizable user setting program withCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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