GAP-43 Polyclonal Antibody, 100ul Tubes Mutations in this gene have

Mutations in this gene have been associated with dystonia

Mutations in this gene are associated with several congenital cardiovascular malformations

This protein has also been reported to have a role in cancer metastasis

they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region

An important paralog of this gene is HAP1

GAP-43 Polyclonal Antibody, 100ul Tubes Mutations in this gene haveNeuromodulin encoded by GAP43 has been termed a growth' or plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. Neuromodulin is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for GAP43.