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UBP46 Polyclonal Antibody, 20ul Sample Library Tubes STAT family members are phosphorylated

SKU: 43013862591

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UBP46 Polyclonal Antibody, 20ul Sample Library Tubes STAT family members are phosphorylatedModification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004

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Description

STAT family members are phosphorylated by the receptor associated kinases

The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair

NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing

As such| it may play a role in anti-viral immunity

Multiple transcript variants encoding different isoforms have been found for ARHGAP9

UBP46 Polyclonal Antibody, 20ul Sample Library Tubes STAT family members are phosphorylatedModification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004

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