VATB2 Polyclonal Antibody, 20ul Immune Cell Analysis adds and removes ubiquitin

adds and removes ubiquitin

It plays a role in mediating cell fate decisions during hematopoiesis

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

This protein may play a role in transcription-coupled DNA repair or genetic recombination

The protein is named for Strumpell disease

VATB2 Polyclonal Antibody, 20ul Immune Cell Analysis adds and removes ubiquitinThis gene encodes a component of vacuolar ATPase (V ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor mediated endocytosis, and synaptic vesicle proton gradient generation. V ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain