NF-κB p105(Phospho Ser923) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis In a complex with MAP3K8|

In a complex with MAP3K8| NFKB1/p105 represses MAP3K8-induced MAPK signaling

thyroid hormone receptors and retinoid X receptors

This protein may also play a role in growth a differentiation of certain cancer cells

Several transcript variants encoding different protein isoforms have been found for this gene

The encoded protein contains an N-terminal U2AF ligand motif| a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence| a zinc knuckles domain| and a C-terminal proline-rich domain

NF-κB p105(Phospho Ser923) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis In a complex with MAP3K8|Glycine rich region (GRR) appears to be a critical element in the generation of p50. The C terminus of p105 might be involved in cytoplasmic retention inhibition of DNA binding and transcription activation. NF kappa B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation immunity differentiation cell growth tumorigenesis and apoptosis. NF kappa B is a homo or