APG7 Rabbit Polyclonal Antibody, 100ul Serum Among its related pathways are

Among its related pathways are MicroRNAs in cancer and p53 Pathway (RnD)

Zinc finger protein 420 encoded by ZNF420 is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis

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and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired

APG7 Rabbit Polyclonal Antibody, 100ul Serum Among its related pathways areThis gene encodes an E1 like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53 dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions including axon membrane trafficking axonal homeostasis mitophagy adipose differentiation and hematopoietic stem cell maintenance. Alternative splicing results in multiple