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EKLF Polyclonal Antibody, 50ul Culture Plate Inserts in that its endogenous ligand

SKU: 43489348791

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EUR185.00 EUR224.00

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EKLF Polyclonal Antibody, 50ul Culture Plate Inserts in that its endogenous ligandKLF1 encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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Description

in that its endogenous ligand has not been identified

This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females

or processing transcripts

Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds

growth and differentiation

EKLF Polyclonal Antibody, 50ul Culture Plate Inserts in that its endogenous ligandKLF1 encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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