Rat Oncostatin-M, OSM ELISA Kit, 96T Endonucleases & Exonucleases Mutations in this gene have

Mutations in this gene have been linked with Li-Fraumeni syndrome| a highly penetrant familial cancer phenotype usually associated with inherited mutati

This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E

Positive regulator of cellular mitogenesis of the MAPK signaling pathway

MIA mRNA is present in carcinomas of the colon

regulates the kinase activity

Rat Oncostatin-M, OSM ELISA Kit, 96T Endonucleases & Exonucleases Mutations in this gene haveGrowth regulator. Inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL 6, G CSF and GM CSF from endothelial cells (By similarity). Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.