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CD63 Polyclonal Antibody, 50ul[BT-AP02138] Gene Synthesis Matrix metalloproteinase-16 activates MMP2 by

SKU: 43577962308

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PLN162.00 PLN203.00

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CD63 Polyclonal Antibody, 50ul[BT-AP02138] Gene Synthesis Matrix metalloproteinase-16 activates MMP2 byCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin

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Description

Matrix metalloproteinase-16 activates MMP2 by cleavage

This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin

This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor

Several alternative transcripts encoding different isoforms have been described

which is specific for the small GTPase family member Rac

CD63 Polyclonal Antibody, 50ul[BT-AP02138] Gene Synthesis Matrix metalloproteinase-16 activates MMP2 byCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin

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