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PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging The encoded protein is thought

SKU: 43709289123

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SEK142.00 SEK176.00

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PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging The encoded protein is thoughtThe protein encoded by PMS2 (PMS1 homolog 2, mismatch repair system component) is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL alpha heterodimer. The MutL alpha heterodimer possesses an endonucleolytic

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Description

The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4

it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream

where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle

This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level

Sterilized and non-sterilized versions are available

PMS2/PMS2CL Polyclonal Antibody, 50ul Cell Screening and Imaging The encoded protein is thoughtThe protein encoded by PMS2 (PMS1 homolog 2, mismatch repair system component) is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL alpha heterodimer. The MutL alpha heterodimer possesses an endonucleolytic

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