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Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos This gene encodes a protein

SKU: 43792824249

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Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos This gene encodes a proteinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level

This gene encodes a single-pass membrane protein| which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily

RGS14 encodes a member of the regulator of G-protein signaling family

This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins

The pipet body is translucent and bright white with good fluid flow along the pipet wall

Rb Polyclonal Antibody, 100ul[BT-AP07691] sgRNA Oligos This gene encodes a proteinThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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