GBB3 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been described for this gene

The two genes

The product of P2RY13 (purinergic receptor P2Y13)belongs to the family of G-protein coupled receptors

This member is identified as a 'silent subunit'

Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency

GBB3 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variantsHeterotrimeric guanine nucleotide binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A