SphK2 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation The pyruvate dehydrogenase (PDH) complex

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)

This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias

G Protein-Coupled Receptor 176 is a orphan receptor

a region that includes a cluster of chemokine receptor genes

Mutations in PLCG2 have been found in autoinflammation

SphK2 Polyclonal Antibody, 20ul Polyclonal Antibody Preparation The pyruvate dehydrogenase (PDH) complexSPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1 phosphate. Sphingosine 1 phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance.