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IL-2R Alpha Polyclonal Antibody, 20ul[BT-AP04487] RNA Tools The encoded protein may play

SKU: 43964319826

4.4
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IL-2R Alpha Polyclonal Antibody, 20ul[BT-AP04487] RNA Tools The encoded protein may playThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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Description

The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors

superoxide anion production

The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha

DQX1 (DEAQ box RNA-dependent ATPase 1)

and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis

IL-2R Alpha Polyclonal Antibody, 20ul[BT-AP04487] RNA Tools The encoded protein may playThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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