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DOC10 Rabbit Polyclonal Antibody, 50ul Organelle Studies PEX2 encodes an integral peroxisomal

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DOC10 Rabbit Polyclonal Antibody, 50ul Organelle Studies PEX2 encodes an integral peroxisomalThis gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins which also contain an N terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described.

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Description

PEX2 encodes an integral peroxisomal membrane protein required for peroxisome biogenesis

which are involved in signalling during embryonic development

In particular

interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation

CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit) is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily

DOC10 Rabbit Polyclonal Antibody, 50ul Organelle Studies PEX2 encodes an integral peroxisomalThis gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins which also contain an N terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described.

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