RAGE Polyclonal Antibody, 20ul[BT-AP07639] Gel & Buffers 118A>G allele has been associated

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer

The protein also functions in the regulation of the cell cycle in response to DNA damage

The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine

A/G-specific adenine DNA glycosylase is localized to the nucleus and mitochondria

RAGE Polyclonal Antibody, 20ul[BT-AP07639] Gel & Buffers 118A>G allele has been associatedThe advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non protein coding