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TORC1 Monoclonal Antibody, 50ul[BT-MCA1215] Liquid Handling &Storage Gene Ontology (GO) annotations related

SKU: 44495383130

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SEK162.00 SEK198.00

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TORC1 Monoclonal Antibody, 50ul[BT-MCA1215] Liquid Handling &Storage Gene Ontology (GO) annotations relatedA chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11 19)(q21 p13) with MAML2. The fusion protein consists of the N terminus of CRTC1 joined to the C terminus of MAML2. The reciprocal fusion protein consisting of the N terminus of MAML2 joined to the C terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:

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Description

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription factor activity

The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels

They are plasma membrane proteins containing seven epidermal growth factor-like repeats

It is a secreted protein and exists in either a single chain form or a clipped

and has been implicated in development of prostate cancer cells

TORC1 Monoclonal Antibody, 50ul[BT-MCA1215] Liquid Handling &Storage Gene Ontology (GO) annotations relatedA chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11 19)(q21 p13) with MAML2. The fusion protein consists of the N terminus of CRTC1 joined to the C terminus of MAML2. The reciprocal fusion protein consisting of the N terminus of MAML2 joined to the C terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:

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